Finding Cures for Tropical Diseases: Is Open Source an Answer?
نویسندگان
چکیده
منابع مشابه
Finding Cures for Tropical Diseases: Is Open Source an Answer?
Tropical diseases affect more than 500 million people, one tenth of the world’s population.1 Malaria, for example, kills more than one million people each year.2 And yet, only about one percent of new drugs treat tropical diseases.3 For diseases prevalent in rich countries, patent incentives and commercial pharmaceutical houses have created health innovation systems that are the envy of the wor...
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Computation plays an increasing role in biology. We argue that a new approach, which we call “open source drug discovery,” would significantly reduce the cost of discovering, developing, and manufacturing cures for tropical diseases. First, it would give hundreds of scientists a practical way to donate urgently needed manpower. Second, open source discoveries would not be patented. This would p...
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BACKGROUND Conventional patent-based drug development incentives work badly for the developing world, where commercial markets are usually small to non-existent. For this reason, the past decade has seen extensive experimentation with alternative R&D institutions ranging from private-public partnerships to development prizes. Despite extensive discussion, however, one of the most promising aven...
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ژورنال
عنوان ژورنال: PLoS Medicine
سال: 2004
ISSN: 1549-1676
DOI: 10.1371/journal.pmed.0010056